
Butylated hydroxyanisole
CAS No. 25013-16-5
Butylated hydroxyanisole ( —— )
产品货号. M13735 CAS No. 25013-16-5
丁基羟基茴香醚(BHA)是一种抗氧化剂,由两种异构有机化合物2-叔丁基-4-羟基茴香醚和3-叔丁基-4-羟基茴香醚的混合物组成。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
500MG | ¥340 | 有现货 |
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1G | ¥405 | 有现货 |
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生物学信息
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产品名称Butylated hydroxyanisole
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述丁基羟基茴香醚(BHA)是一种抗氧化剂,由两种异构有机化合物2-叔丁基-4-羟基茴香醚和3-叔丁基-4-羟基茴香醚的混合物组成。
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产品描述Butylated hydroxyanisole (BHA) is an antioxidant consisting of a mixture of two isomeric organic compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.
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体外实验Cell Proliferation Assay Cell Line:NHA-SV40LT cellsConcentration:0 μM, 25 μM, 50 μM, 75 μM, 100 μM Incubation Time:48 hours Result:Exerted antiproliferative effects.Cell Cycle Analysis Cell Line:NHA-SV40LT cells Concentration:100 μM Incubation Time:48 hours Result:Downregulated the typical cell proliferative signaling pathways, phosphoinositide 3-kinase/protein kinase B and extracellular signal-regulated kinase 1/2.Apoptosis Analysis Cell Line:NHA-SV40LT cells Concentration:100 μM Incubation Time:48 hours Result:Increased the levels of pro-apoptotic proteins, such as BAX, cytochrome c, cleaved caspase 3, and cleaved caspase 9, and decreased the level of anti-apoptotic protein BCL-XL.Western Blot AnalysisCell Line:NHA-SV40LT cells Concentration:100 μM Incubation Time:48 hours Result:Increased the expression of pro-apoptotic proteins and decreased the levels of anti-apoptotic proteins. Asterisks show significant effects.
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体内实验Animal Model:Five-week-old C57BL/6 mice (WT and Nrf2-/-)Dosage:200 mg/kg Administration:Oral gavage, daily, for three days Result:Increased Nqo1 staining in hepatocytes, predominately in the pericentral region.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域Other Indications
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适应症——
化学信息
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CAS Number25013-16-5
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分子量180.25
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分子式C11H16O2
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纯度>98% (HPLC)
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溶解度DMSO: 10 mM
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SMILESCOC1=CC(=C(O)C=C1)C(C)(C)C
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Lam LK, et al. J Med Chem. 1979 May; 22(5):569-7
产品手册




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